Fig. 1 · Structure
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Lin28-let-7 antagonist 1
Lin28-let-7 Antagonist
Lin28-let-7 antagonist 1 is a potent disruptor of the Lin28/pre-let-7 interaction, targeting Lin28A's binding to pre-let-7a-2 with an IC50 of 8 μM. This compound demonstrates significant inhibitory effects on cellular proliferation in human cancer cells. It serves as a valuable tool for research in cancer biology and the regulatory mechanisms of microRNA pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 108825-65-6 |
| Applications | Lin28-let-7 Antagonist |
| Formula | C15H15N5O |
| Molecular Weight | 281.32 |
| SMILES | CN(C(C)=O)C1=CC=CC(C2=NN3C(C)=NN=C3C=C2)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.