Fig. 1 · Structure
Documents & Downloads
Linaprazan glurate
Acid-Lowering Agent
Linaprazan glurate is an orally active prodrug of Linaprazan that functions as a potassium-competitive inhibitor of gastric acid secretion. Its primary mechanism involves the selective inhibition of gastric H⁺/K⁺-ATPase, demonstrating a potent inhibitory effect with an IC50 of 436.2 nM. Linaprazan glurate is rapidly converted into its active form, making it effective for studies focused on conditions such as erosive esophagitis (EE) where acid reduction is critical.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1228559-81-6 |
| Applications | Acid-Lowering Agent |
| Formula | C26H32N4O5 |
| Molecular Weight | 480.56 |
| Synonyms | X842 |
| SMILES | O=C(CCCC(OCCNC(C1=CN2C(C)=C(C)N=C2C(NCC3=C(C)C=CC=C3C)=C1)=O)=O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.