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Linustedastatum

Catalog No.: A68988
HSD17B1 Inhibitor
Linustedastatum is an orally active inhibitor of hydroxysteroid 17-beta dehydrogenase 1 (HSD17B1). This compound exhibits significant biological activity by modulating the biosynthesis of estrogens, making it a valuable tool for research applications related to endometriosis. Its mechanism of action provides insights into hormonal pathways and potential therapeutic targets in gynecological disorders.
Linustedastatum 2254299-48-2 HSD17B1 Inhibitor
Grouped product items
Size Price Stock Qty
5mg
$1,010.00
In stock
10mg
$1,660.00
In stock
25mg
$3,320.00
In stock
50mg
$4,860.00
In stock
100mg
$7,110.00
In stock
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Free Delivery on orders over $500
Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionLinustedastatum is an orally active inhibitor of hydroxysteroid 17-beta dehydrogenase 1 (HSD17B1). This compound exhibits significant biological activity by modulating the biosynthesis of estrogens, making it a valuable tool for research applications related to endometriosis. Its mechanism of action provides insights into hormonal pathways and potential therapeutic targets in gynecological disorders.
Product Information
Catalog NumA68988
FormulaC26H29F2N3O2
Molecular Weight453.52
CAS Number2254299-48-2
SMILESC[C@@]12[C@]([C@@H](C/C2=N\O)CCC(NC3=CC=C(C=N3)F)=O)([H])[C@@]4([H])[C@@](CC1)([H])C5=CC=CC(F)=C5CC4
SynonymsLinustedastat; FOR-6219; OG-6219
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Metabolism > 17β-HSD