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Lipid C2

LNP

Lipid C2 is an ionizable cationic lipid designed for the formation of lipid nanoparticles (LNP) utilized in mRNA delivery. These LNPs efficiently target the liver and spleen in vivo, enhancing gene expression while sparing other vital organs. In a CT26 murine model of Epstein-Barr virus (EBV) infection, LNPs containing Lipid C2 and mRNA encoding the EBV latent membrane protein 2 (LMP-2), when used alongside an anti-PD-1 antibody, demonstrated significant tumor suppression, reduced T cell exhaustion, and increased populations of memory T cells. This makes Lipid C2 a valuable tool for innovative therapeutic strategies in cancer immunology.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	3003022-09-8
Applications	LNP
Formula	C₇₀H₁₄₂N₆O₆
Molecular Weight	1163.91
SMILES	O=C(CCN1CCN(CC1)CCC(NCCN(CC(CCCCCCCCCCCC)O)CC(CCCCCCCCCCCC)O)=O)NCCN(CC(CCCCCCCCCCCC)O)CC(CCCCCCCCCCCC)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.