Fig. 1 · Structure
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Lithium citrate
N-acetyl aspartate Inhibitor
Lithium citrate acts as an inhibitor of N-acetylaspartate (NAA), targeting metabolic disturbances associated with Canavan disease. This autosomal recessive leukodystrophy arises from mutations in the aspartate acylase (ASPA) gene, leading to elevated levels of NAA. By reducing excess NAA, lithium citrate is utilized in research to investigate treatment avenues for this condition and its associated neurological deficits.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 919-16-4 |
| Applications | N-acetyl aspartate Inhibitor |
| Formula | C6H5Li3O7 |
| Molecular Weight | 209.92 |
| Synonyms | Litarex |
| SMILES | O=C(CC(C(O[Li])=O)(CC(O[Li])=O)O)O[Li] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.