Fig. 1 · Structure
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LM10
TDO Inhibitor
LM10 is a potent inhibitor of tryptophan 2,3-dioxygenase (TDO), an enzyme involved in the degradation of tryptophan via the kynurenine pathway. By inhibiting TDO, LM10 may alter tryptophan metabolism and has potential applications in cancer research and therapeutic development. This reagent can be utilized to investigate the role of TDO in tumor progression and immune modulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1316695-35-8 |
| Applications | TDO Inhibitor |
| Formula | C11H8FN5 |
| Molecular Weight | 229.22 |
| SMILES | FC1=CC2=C(C=C1)C(/C=C/C3=NN=NN3)=CN2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.