Fig. 1 · Structure

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LmCPB-IN-1

LmCPB Inhibitor

LmCPB-IN-1 is a potent and reversible covalent inhibitor of Leishmania mexicana cysteine protease B (LmCPB), exhibiting a high pKi of 9.7. This compound demonstrates effective inhibition of LmCPB activity, making it a valuable tool for studying Leishmania infections and developing potential therapeutic strategies. Its selectivity and potency support its use in research applications focused on cysteine protease enzymology and parasitic disease mechanisms.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2151025-98-6
Applications LmCPB Inhibitor
Formula C18H30N6O2
Molecular Weight 362.47
SMILES
CC(C[C@@H](C(N(N(C#N)C)C)=O)NC(C1=CC(C(C)(C)C)=NN1C)=O)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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