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Biological Activity
LMD-009 is a selective CCR8 nonpeptide agonist. LMD-009 mediates chemotaxis, inositol phosphate accumulation, and calcium release in high potencies with EC50s from 11 to 87 nM.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 21.2 mL | 106.02 mL | 212.05 mL |
0.5 mM | 4.24 mL | 21.2 mL | 42.41 mL |
1 mM | 2.12 mL | 10.6 mL | 21.2 mL |
5 mM | 0.42 mL | 2.12 mL | 4.24 mL |
*The above data is based on the productmolecular weight 471.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A18643 |
---|---|
Actions | Agonist |
CAS No. | 950195-51-4 |
Formula | C29H33N3O3 |
M. Wt | 471.59 |
Purity | >98% |
Synonyms | LMD 009, LMD009 |
SMILES | O=C1NCN(CCC2=CC=CC=C2)C13CCN(CC4=CC=CC(OC5=CC=CC=C5OC)=C4)CC3 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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