Lobelanidine is a selective antagonist of nicotinic acetylcholine receptors (nAChR), effectively inhibiting the α7 nAChR response as well as the α3β2/α3β4 nAChR responses, with IC50 values of 2.8 μM and 8.2 μM, respectively. This compound serves as a valuable tool for investigating the role of nAChRs in neuronal signaling and various neurological disorders. Its pharmacological properties make it suitable for research applications in neurobiology, drug discovery, and toxicology studies.
Lobelanidine is a selective antagonist of nicotinic acetylcholine receptors (nAChR), effectively inhibiting the α7 nAChR response as well as the α3β2/α3β4 nAChR responses, with IC50 values of 2.8 μM and 8.2 μM, respectively. This compound serves as a valuable tool for investigating the role of nAChRs in neuronal signaling and various neurological disorders. Its pharmacological properties make it suitable for research applications in neurobiology, drug discovery, and toxicology studies.
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