Fig. 1 · Structure
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Lobeline sulfate
Nicotinic Receptor Agonist
Lobeline sulfate is a potent nicotinic receptor agonist known for its ability to penetrate the blood-brain barrier. It enhances dopamine release by inhibiting dopamine uptake into synaptic vesicles and modifying presynaptic dopamine storage. This compound has demonstrated efficacy in supporting smoking cessation efforts, making it a valuable tool for research in addiction and neuropharmacology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 134-64-5 |
| Applications | Nicotinic Receptor Agonist |
| Formula | C44H56N2O8S |
| Molecular Weight | 772.99 |
| Synonyms | α-Lobeline sulfate; L-Lobeline sulfate |
| SMILES | CN1[C@@H](CC(C2=CC=CC=C2)=O)CCC[C@H]1C[C@H](O)C3=CC=CC=C3.CN4[C@@H](CC(C5=CC=CC=C5)=O)CCC[C@H]4C[C@H](O)C6=CC=CC=C6.O=S(O)(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.