Fig. 1 · Structure
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Lomedeucitinib
TYK2 Inhibitor
Lomedeucitinib is a selective inhibitor of tyrosine protein kinase 2 (TYK2), disrupting the signaling pathways associated with immune response and inflammation. This compound exhibits significant anti-inflammatory and immunomodulatory activities, making it a valuable tool in researching autoimmune diseases and other inflammatory conditions. Its inhibition of TYK2 has potential applications in understanding the mechanisms underlying various pathologies and developing targeted therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2328068-29-5 |
| Applications | TYK2 Inhibitor |
| Formula | C18H17D3N6O4S |
| Molecular Weight | 419.47 |
| Synonyms | BMS-986322 |
| SMILES | O=C(C1=NN=C(NC([C@@H]2CC23CC3)=O)C=C1NC4=NC=CC=C4S(=O)(C)=O)NC([2H])([2H])[2H] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.