Losartan-d9 is a deuterated form of Losartan, which serves as an angiotensin II receptor antagonist. It effectively competes with angiotensin II for binding to AT1 receptors, demonstrating an IC50 value of 20 nM. This stable isotope is valuable in pharmacokinetic studies and metabolic research, providing insights into drug metabolism and pharmacodynamics.
Losartan-d9 is a deuterated form of Losartan, which serves as an angiotensin II receptor antagonist. It effectively competes with angiotensin II for binding to AT1 receptors, demonstrating an IC50 value of 20 nM. This stable isotope is valuable in pharmacokinetic studies and metabolic research, providing insights into drug metabolism and pharmacodynamics.
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