Losartan

Catalog No.: A17510
Angiotensin II receptor antagonist
Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM.
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Product Name Price Stock Qty
Losartan 500mg
$50.00
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Biological Activity
Discription Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM.
Product Information
Catalog Num A17510
Formula C22H23ClN6O
Molecular Weight 422.91
CAS Number 114798-26-4
SMILES OCC1=C(Cl)N=C(CCCC)N1CC2=CC=C(C3=CC=CC=C3C4=NNN=N4)C=C2
Synonyms Losartan; DUP 89; DUP-89; DUP89;
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 76 mg/mL (179.7 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.65 mL 118.23 mL 236.46 mL
0.5 mM 4.73 mL 23.65 mL 47.29 mL
1 mM 2.36 mL 11.82 mL 23.65 mL
5 mM 0.47 mL 2.36 mL 4.73 mL
Useful Calculator

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