Losartan

Catalog No.: A17510

Angiotensin II receptor antagonist

Losartan

Losartan Chemical Structure

CAS NO. 114798-26-4

Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM.

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500 mg
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Biological Activity

Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.65 mL 118.23 mL 236.46 mL
0.5 mM 4.73 mL 23.65 mL 47.29 mL
1 mM 2.36 mL 11.82 mL 23.65 mL
5 mM 0.47 mL 2.36 mL 4.73 mL

*The above data is based on the productmolecular weight 422.91. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17510
Actions Antagonist
M. Wt 422.91
Formula C22H23ClN6O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 114798-26-4
Synonyms Losartan; DUP 89; DUP-89; DUP89;
SMILES OCC1=C(Cl)N=C(CCCC)N1CC2=CC=C(C3=CC=CC=C3C4=NNN=N4)C=C2

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