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Lotixparib

PARP-1 Inhibitor

Lotixparib is a potent inhibitor of poly(ADP-ribose) polymerase-1 (PARP-1), a key enzyme involved in DNA damage repair. This compound demonstrates cytoprotective effects, offering potential therapeutic applications in retinal diseases. Lotixparib is valuable for research focused on PARP-1-related conditions and mechanisms underlying DNA repair pathways.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2640677-63-8
Applications	PARP-1 Inhibitor
Formula	C₂₃H₂₃FN₄O
Molecular Weight	390.45
SMILES	N#CC1=CC=C(N2CCN(CCCC3=CC4=C(C(N3)=O)C(F)=CC=C4)CC2)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.