Fig. 1 · Structure
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Lotrafiban
platelet GPIIb/IIIa blocker
Lotrafiban is an orally active antagonist of the platelet GPIIb/IIIa receptor, designed for research into thrombotic disorders. It inhibits platelet aggregation, making it valuable for studies related to coronary artery disease and cerebrovascular conditions. This compound is instrumental in exploring the therapeutic potential of GPIIb/IIIa inhibition in cardiovascular research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 171049-14-2 |
| Applications | platelet GPIIb/IIIa blocker |
| Formula | C23H32N4O4 |
| Molecular Weight | 428.52 |
| Synonyms | SB-214857 |
| SMILES | O=C1N(C)CC2=CC(C(N3CCC(C4CCNCC4)CC3)=O)=CC=C2N[C@H]1CC(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.