Lovastatin (Mevacor)

Catalog No.: A11877

HMG-CoA reductase inhibitor

Lovastatin (Mevacor)

Lovastatin (Mevacor) Chemical Structure

CAS NO. 75330-75-5

Lovastatin is an inhibitor of HMG-CoA reductase with IC50 of 3.4 nM, used for lowering cholesterol (hypolipidemic agent).

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Warning WARNING: Attention California Residents: This product can expose you to chemicals including Lovastatin (Mevacor) , which is known to the State of California to cause cancer and birth defects or other reproductive harm. For more information, go to www.P65Warnings.ca.gov
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Lovastatin is an inhibitor of HMG-CoA reductase with IC50 of 3.4 nM, used for lowering cholesterol (hypolipidemic agent).
HMG-CoA reductase (Cell-free assay)
3.4 nM
In vitro (25°C) DMSO 8 mg/mL (19.77 mM)
Water <1 mg/mL (<1 mM)
Ethanol 6 mg/mL (14.83 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.72 mL 123.6 mL 247.19 mL
0.5 mM 4.94 mL 24.72 mL 49.44 mL
1 mM 2.47 mL 12.36 mL 24.72 mL
5 mM 0.49 mL 2.47 mL 4.94 mL

*The above data is based on the productmolecular weight 404.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11877
Actions Inhibitor
M. Wt 404.54
Formula C24H36O5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 75330-75-5
SMILES CC[[email protected]](C)C(=O)O[[email protected]]1C[[email protected]](C=C2[[email protected]]1[[email protected]]([[email protected]](C=C2)C)CC[[email protected]@H]3C[[email protected]](CC(=O)O3)O)C

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