Loxapine Succinate

Catalog No.: A17347

D2DR and D4DR inhibitor

Loxapine Succinate

Loxapine Succinate Chemical Structure

CAS NO. 27833-64-3

Loxapine Succinate is a D2DR and D4DR inhibitor and serotonergic receptor antagonist. Loxapine succinate is an antipsychotic agent used in schizophrenia.

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500 mg
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Biological Activity

Loxapine Succinate is a D2DR and D4DR inhibitor and serotonergic receptor antagonist. Loxapine succinate is an antipsychotic agent used in schizophrenia.
In vitro DMSO 80 mg/mL (179.41 mM)
Water Insoluble
Ethanol 2 mg/mL (4.48 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.43 mL 112.13 mL 224.27 mL
0.5 mM 4.49 mL 22.43 mL 44.85 mL
1 mM 2.24 mL 11.21 mL 22.43 mL
5 mM 0.45 mL 2.24 mL 4.49 mL

*The above data is based on the productmolecular weight 445.9. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17347
Actions Inhibitor
CAS No. 27833-64-3
Formula C22H24ClN3O5
M. Wt 445.9
Solubility DMSO
Purity >98%
Synonyms Loxapine Succinate; Loxapine succinate salt; Loxapac; Cloxazepin; Daxolin; Maleate, Loxipine; Oxilapine; Succinate, Loxapine;
SMILES CN1CCN(CC1)C2=NC3=CC=CC=C3OC4=C2C=C(C=C4)Cl.C(CC(=O)O)C(=O)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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