Biological Activity
Loxapine Succinate is a D2DR and D4DR inhibitor and serotonergic receptor antagonist. Loxapine succinate is an antipsychotic agent used in schizophrenia.
In vitro | DMSO | 80 mg/mL (179.41 mM) | |
Water | Insoluble | ||
Ethanol | 2 mg/mL (4.48 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 22.43 mL | 112.13 mL | 224.27 mL |
0.5 mM | 4.49 mL | 22.43 mL | 44.85 mL |
1 mM | 2.24 mL | 11.21 mL | 22.43 mL |
5 mM | 0.45 mL | 2.24 mL | 4.49 mL |
*The above data is based on the productmolecular weight 445.9. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A17347 |
---|---|
Actions | Inhibitor |
CAS No. | 27833-64-3 |
Formula | C22H24ClN3O5 |
M. Wt | 445.9 |
Solubility | DMSO |
Purity | >98% |
Synonyms | Loxapine Succinate; Loxapine succinate salt; Loxapac; Cloxazepin; Daxolin; Maleate, Loxipine; Oxilapine; Succinate, Loxapine; |
SMILES | CN1CCN(CC1)C2=NC3=CC=CC=C3OC4=C2C=C(C=C4)Cl.C(CC(=O)O)C(=O)O |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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