Fig. 1 · Structure
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LOXL2-IN-1
LOXL2 Inhibitor
LOXL2-IN-1 is a selective inhibitor of lysyl oxidase-like 2 (LOXL2) with an IC50 value of less than 300 nM. This compound exhibits significant anti-fibrotic properties, making it a valuable tool for researching fibrotic diseases and mechanisms of extracellular matrix regulation. Its oral bioavailability enhances its utility in in vivo studies aimed at elucidating the role of LOXL2 in various pathophysiological conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2125665-47-4 |
| Applications | LOXL2 Inhibitor |
| Formula | C21H25FN4O2S |
| Molecular Weight | 416.51 |
| SMILES | NC/C=C(CN1C2=CC=CN=C2C(CC3=CN=C(C=C3)S(C)(=O)=O)=C1C(C)C)\F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.