LP 12 hydrochloride is a potent and selective agonist of the 5-HT7 receptor, exhibiting a Ki value of 0.13 nM. This compound demonstrates significant selectivity for the 5-HT7 receptor compared to D2, 5-HT1A, and 5-HT2A receptors, with Ki values of 224 nM, 60.9 nM, and >1000 nM, respectively. LP 12 hydrochloride is valuable for research applications focusing on serotonin receptor signaling and its implications in neuropharmacology.
LP 12 hydrochloride is a potent and selective agonist of the 5-HT7 receptor, exhibiting a Ki value of 0.13 nM. This compound demonstrates significant selectivity for the 5-HT7 receptor compared to D2, 5-HT1A, and 5-HT2A receptors, with Ki values of 224 nM, 60.9 nM, and >1000 nM, respectively. LP 12 hydrochloride is valuable for research applications focusing on serotonin receptor signaling and its implications in neuropharmacology.
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