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Biological Activity
LP-211 is a a selective agonist of the serotonin 5-HT7 receptor with a Ki value of 0.58 nM at rat cloned 5-HT7 receptors, and >300-fold selectivity over the 5-HT1A receptor.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.43 mL | 107.15 mL | 214.3 mL |
| 0.5 mM | 4.29 mL | 21.43 mL | 42.86 mL |
| 1 mM | 2.14 mL | 10.72 mL | 21.43 mL |
| 5 mM | 0.43 mL | 2.14 mL | 4.29 mL |
*The above data is based on the productmolecular weight 466.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A16898 |
|---|---|
| Actions | Agonist |
| CAS No. | 1052147-86-0 |
| Formula | C30H34N4O |
| M. Wt | 466.63 |
| Purity | >98% |
| Synonyms | LP211, LP 211 |
| SMILES | O=C(NCC1=CC=C(C#N)C=C1)CCCCCN2CCN(C3=CC=CC=C3C4=CC=CC=C4)CC2 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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