Fig. 1 · Structure

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LP-533401 hydrochloride

Tryptophan Hydroxylase Inhibitor

LP-533401 hydrochloride is an inhibitor of tryptophan hydroxylase 1, a key enzyme in serotonin biosynthesis. By modulating serotonin production in the gut, this compound serves as a valuable tool for investigating the role of serotonin in gastrointestinal physiology and associated disorders. Its applications extend to understanding the pathophysiology of conditions related to serotonin dysregulation, including mood disorders and gastrointestinal diseases.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1040526-12-2
Applications Tryptophan Hydroxylase Inhibitor
Formula C27H23ClF4N4O3
Molecular Weight 562.94
SMILES
N[C@@H](CC1=CC=C(C2=NC(N)=NC(OC(C3=CC=C(C4=CC=CC(F)=C4)C=C3)C(F)(F)F)=C2)C=C1)C(O)=O.[H]Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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