Fig. 1 · Structure
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LP44 hydrochloride
5-HT7 Agonist
LP44 hydrochloride is a selective agonist of the 5-HT7 receptor, exhibiting a Ki value of 0.22 nM. This compound induces a dose-dependent hypothermic response when administered via intracerebroventricular injection, although it does not elicit significant hypothermia when given intraperitoneally. LP44 hydrochloride is valuable for studying the physiological roles of 5-HT7 receptors and their potential therapeutic applications in neurological research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 824958-12-5 |
| Applications | 5-HT7 Agonist |
| Formula | C27H38ClN3OS |
| Molecular Weight | 488.13 |
| SMILES | O=C(CCCCCN1CCN(C(C=CC=C2)=C2SC)CC1)NC3C4=CC=CC=C4CCC3.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.