LP44 hydrochloride is a selective agonist of the 5-HT7 receptor, exhibiting a Ki value of 0.22 nM. This compound induces a dose-dependent hypothermic response when administered via intracerebroventricular injection, although it does not elicit significant hypothermia when given intraperitoneally. LP44 hydrochloride is valuable for studying the physiological roles of 5-HT7 receptors and their potential therapeutic applications in neurological research.
LP44 hydrochloride is a selective agonist of the 5-HT7 receptor, exhibiting a Ki value of 0.22 nM. This compound induces a dose-dependent hypothermic response when administered via intracerebroventricular injection, although it does not elicit significant hypothermia when given intraperitoneally. LP44 hydrochloride is valuable for studying the physiological roles of 5-HT7 receptors and their potential therapeutic applications in neurological research.
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