Fig. 1 · Structure
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LRAT-IN-1
LRAT Inhibitor
LRAT-IN-1 is a potent inhibitor of the enzyme retinol acyltransferase (LRAT), exhibiting an IC50 value of 21.1 μM. This compound functions by preventing the esterification of retinol, thereby increasing the free retinol concentration in the skin. LRAT-IN-1 is of significant interest in anti-aging research, particularly in the development of cosmetic formulations aimed at enhancing skin appearance and rejuvenation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2820064-05-7 |
| Applications | LRAT Inhibitor |
| Formula | C27H47N5O5S2 |
| Molecular Weight | 585.82 |
| SMILES | CCCCCCCCCCCCS(=O)(NC(CC1=CC=CC(C(N)=N)=C1)C(N2CCN(S(C)(=O)=O)CC2)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.