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LRRK2-IN-13

LRRK2 Inhibitor

LRRK2-IN-13 is a potent inhibitor of Leucine-rich repeat kinase 2 (LRRK2), exhibiting an IC50 of 0.57 nM. This compound possesses brain-penetrating properties, making it particularly useful for in vivo studies. LRRK2-IN-13 is primarily utilized in research related to neurodegenerative diseases, including Parkinson's disease, to explore mechanisms of kinase inhibition and elucidate potential therapeutic pathways.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3032733-17-5
Applications	LRRK2 Inhibitor
Formula	C₁₉H₁₉ClN₈O₂
Molecular Weight	426.86
SMILES	CC1=C(NC2=NC3=C4C=N2)C(OCCCN3N=C4Cl)=NN1C5=CC=C(C)N=C5OC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.