LSN 3213128

Catalog No.: A19472

AICARFT inhibitor

LSN 3213128

LSN 3213128 Chemical Structure

CAS NO. 1941211-99-9

LSN 3213128 is a selective, nonclassical, orally bioavailable antifolate with potent and specific inhibitory activity for aminoimidazole-4-carboxamide ribonucleotide formyltransferase (AICARFT), with IC50 of 16 nM for AICARFT enzyme inhibiton and 19 nM in cells. Anti-tumor activity.

Availability: In stock

Package Price Qty
1 mg
$320.00
5 mg
$960.00
10 mg
$1,600.00
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Biological Activity

LSN 3213128 is a selective, nonclassical, orally bioavailable antifolate with potent and specific inhibitory activity for aminoimidazole-4-carboxamide ribonucleotide formyltransferase (AICARFT), with IC50 of 16 nM for AICARFT enzyme inhibiton and 19 nM in cells. Anti-tumor activity.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.42 mL 122.11 mL 244.22 mL
0.5 mM 4.88 mL 24.42 mL 48.84 mL
1 mM 2.44 mL 12.21 mL 24.42 mL
5 mM 0.49 mL 2.44 mL 4.88 mL

*The above data is based on the productmolecular weight 409.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A19472
Actions Inhibitor
M. Wt 409.46
Formula C17H16FN3O4S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1941211-99-9
Synonyms LSN3213128, LSN-3213128
SMILES O=C1NC=CC2=C1C=C(NS(=O)(C3=CC=C(N4CC[[email protected]@H](O)C4)S3)=O)C(F)=C2

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