Fig. 1 · Structure

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LTK-14A

H4K5 Butyrylation Inhibitor

LTK-14A is a selective inhibitor of histone butyrylation, specifically targeting H4K5. This compound effectively suppresses the butyrylation process without impacting acetylation levels, leading to downregulation of proadipogenic gene expression. As a result, LTK-14A plays a significant role in inhibiting adipogenesis, making it a valuable tool for research in obesity and related metabolic disorders.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 71118-00-8
Applications H4K5 Butyrylation Inhibitor
Formula C40H54O6
Molecular Weight 630.85
SMILES
O=C([C@]1(C(C)2C)C/C=C(C)\C)[C@@](C[C@H]2C/C=C(C)/C)(C[C@@H]3C/C=C(C)\C)C(OC(C)3C)=C(C1=O)C(C(C=C4)=CC(OC)=C4OC)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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