Fig. 1 · Structure
Documents & Downloads
Lu AA33810
NYP Y5 Antagonist
Lu AA33810 is a selective antagonist of the neuropeptide Y5 receptor, demonstrating a high affinity with a Ki of 1.5 nM for the rat receptor. This compound is orally active and penetrates the blood-brain barrier, making it suitable for neurological studies. Lu AA33810 exhibits notable anxiolytic and antidepressant-like effects, providing valuable insights for research in psychiatric disorders and neuropharmacology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 304008-29-5 |
| Applications | NYP Y5 Antagonist |
| Formula | C19H25N3O2S3 |
| Molecular Weight | 423.62 |
| SMILES | CS(NC[C@@H](CC1)CC[C@H]1NC2=NC3=C(S2)CCSC4=CC=CC=C34)(=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.