Lu AF11205

Catalog No.: A61861
mGluR Agonist
Lu AF11205 is a positive allosteric modulator of the mGlu5 receptor, enhancing its activity through a unique mechanism. This compound has demonstrated potent biological activity and is useful in studying mGlu5 receptor involvement in various neurological processes. Research applications include examining its effects in cellular models that express mGlu5 receptors, providing insights into potential therapeutic pathways for neurological disorders.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionLu AF11205 is a positive allosteric modulator of the mGlu5 receptor, enhancing its activity through a unique mechanism. This compound has demonstrated potent biological activity and is useful in studying mGlu5 receptor involvement in various neurological processes. Research applications include examining its effects in cellular models that express mGlu5 receptors, providing insights into potential therapeutic pathways for neurological disorders.
Product Information
Catalog NumA61861
FormulaC17H16N2OS
Molecular Weight296.39
CAS Number1290133-16-2
SMILESO=C(N1CCCCC1)C2=CN=C(S2)C#CC3=CC=CC=C3
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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