Fig. 1 · Structure
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Lu AF11205
mGluR Agonist
Lu AF11205 is a positive allosteric modulator of the mGlu5 receptor, enhancing its activity through a unique mechanism. This compound has demonstrated potent biological activity and is useful in studying mGlu5 receptor involvement in various neurological processes. Research applications include examining its effects in cellular models that express mGlu5 receptors, providing insights into potential therapeutic pathways for neurological disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 1290133-16-2 |
| Applications | mGluR Agonist |
| Formula | C17H16N2OS |
| Molecular Weight | 296.39 |
| SMILES | O=C(N1CCCCC1)C2=CN=C(S2)C#CC3=CC=CC=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.