Fig. 1 · Structure

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LUF6283

HCA(2) Agonist

LUF6283 is a potent, orally active partial agonist of the hydroxycarboxylic acid receptor 2 (HCA(2)), exhibiting a Ki value of 0.55 µM. It demonstrates lipid-lowering properties similar to niacin while minimizing the adverse effect of cutaneous flushing. This compound is valuable in research focused on metabolic disorders and cardiovascular health, providing insights into the modulation of lipid metabolism through HCA(2) activation.

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Specifications

Manufacturer Adooq Bioscience
Actions Partial Agonist
CAS Number 92933-48-7
Applications HCA(2) Agonist
Formula C8H12N2O2
Molecular Weight 168.19
SMILES
O=C(C1=NNC(CCCC)=C1)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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