LUF8100

Name: LUF8100
Brand: Adooq Bioscience
SKU: A59555
Rating: 5 (288 reviews)

Catalog No.: A59555

CCR2/CCR5 Antagonist

LUF8100 is a dual-target antagonist of CCR2 and CCR5, exhibiting pKi values of 5.23 for CCR2 and 4.97 for CCR5. This compound demonstrates significant potential in modulating immune responses and has relevance in cancer research, allowing for the investigation of immune homeostasis and potential therapeutic applications in pathologies driven by these chemokine receptors.

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LUF8100 2954281-30-0 CCR2/CCR5 Antagonist

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Biological Activity

Description	LUF8100 is a dual-target antagonist of CCR2 and CCR5, exhibiting pKi values of 5.23 for CCR2 and 4.97 for CCR5. This compound demonstrates significant potential in modulating immune responses and has relevance in cancer research, allowing for the investigation of immune homeostasis and potential therapeutic applications in pathologies driven by these chemokine receptors.

Product Information

Catalog Num	A59555
Formula	C18H18ClF3N2O2S
Molecular Weight	418.86
CAS Number	2954281-30-0
SMILES	O=S(NC1=CC(N2CCCCC2)=CC=C1)(C3=CC=C(Cl)C(C(F)(F)F)=C3)=O

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