Fig. 1 · Structure

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Lupanine hydrochloride

nAChR Inhibitor

Lupanine hydrochloride is a natural ketonic derivative of Sparteine, functioning as a nicotinic acetylcholine receptor (nAChR) inhibitor. It demonstrates binding affinity for the nAChR with a Ki value of 500 nM, indicating its potential role in modulating cholinergic signaling. This compound is suitable for research applications related to neuromuscular transmission and ganglioplegic activity.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 1025-39-4
Applications nAChR Inhibitor
Formula C15H25ClN2O
Molecular Weight 284.82
Synonyms D-Lupanine hydrochloride
SMILES
O=C1N2[C@]([C@](C3)([H])CN(CCCC4)[C@]4([H])[C@]3([H])C2)([H])CCC1.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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