Fig. 1 · Structure
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Lurasidone metabolite 14326
Lurasidone Metabolite
Lurasidone metabolite 14326 is an active minor metabolite of Lurasidone, formed through CYP3A4-mediated metabolism. This compound exhibits significant receptor-binding characteristics, acting as an antagonist at the dopamine D2 receptor and the serotonin 5-HT2A and 5-HT7 receptors, while functioning as a partial agonist at the serotonin 5-HT1A receptor. Lurasidone metabolite 14326 serves as a valuable tool in the research of schizophrenia and bipolar depression, providing insights into the pharmacological mechanisms underlying these conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 186204-33-1 |
| Applications | Lurasidone Metabolite |
| Formula | C28H36N4O3S |
| Molecular Weight | 508.68 |
| SMILES | O=C([C@]([C@@H]1C[C@H](O)[C@H]2C1)([H])[C@]2([H])C3=O)N3C[C@H]4[C@H](CN(CC5)CCN5C6=NSC7=C6C=CC=C7)CCCC4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.