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Lusvertikimab
Lusvertikimab (OSE-127) is a humanized monoclonal antibody that targets the interleukin-7 receptor (IL7R). This antibody uniquely binds to IL7R without being internalized by the target cells, effectively inhibiting IL7R heterodimerization and the subsequent downstream signaling pathways. Lusvertikimab demonstrates anti-leukemic properties and holds significant potential for research in B cell precursor acute lymphoblastic leukemia (BCP-ALL), making it a valuable tool for studies aimed at understanding and potentially treating this condition.
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Biological Activity
Product Details
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2375835-91-7 |
| Molecular Weight | 145640 |
| Synonyms | OSE-127 |
Storage
Store lyophilized at -20°C, keep desiccated.
In lyophilized form, the antibody is stable for 36 months.
After reconstitution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.