LUT014

Catalog No.: A19449

B-Raf inhibitor

LUT014

LUT014 Chemical Structure

CAS NO. 2274819-46-2

LUT014 is a B-Raf inhibitor with an IC50 of 11.7 nM, and developed to reduce dose-limiting acneiform lesions associated EGFR Inhibitors treatment. Extracted from patent WO 2019026065A2 .

Availability: In stock

Package Price Qty
5 mg
$225.00
10 mg
$380.00
50 mg
$1,140.00
100 mg
$1,940.00
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Biological Activity

LUT014 is a B-Raf inhibitor with an IC50 of 11.7 nM, and developed to reduce dose-limiting acneiform lesions associated EGFR Inhibitors treatment. Extracted from patent WO 2019026065A2 .
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.92 mL 94.61 mL 189.22 mL
0.5 mM 3.78 mL 18.92 mL 37.84 mL
1 mM 1.89 mL 9.46 mL 18.92 mL
5 mM 0.38 mL 1.89 mL 3.78 mL

*The above data is based on the productmolecular weight 528.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A19449
Actions Inhibitor
M. Wt 528.49
Formula C27H19F3N8O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 2274819-46-2
Synonyms LUT 014, LUT-014
SMILES FC(F)(F)OC1=CC(NC2=NC=CC3=C2C=CC(C)=C3NC4=NC=CC=C4C5=C6N=CNC6=NC=N5)=CC=C1

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