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Biological Activity
LXR-623 is a brain-penetrant partial LXRα and full LXRβ agonist, with IC50s of 24 nM and 179 nM, respectively.
| In vitro | DMSO | 76 mg/mL (179.76 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 76 mg/mL (179.76 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.65 mL | 118.26 mL | 236.53 mL |
| 0.5 mM | 4.73 mL | 23.65 mL | 47.31 mL |
| 1 mM | 2.37 mL | 11.83 mL | 23.65 mL |
| 5 mM | 0.47 mL | 2.37 mL | 4.73 mL |
*The above data is based on the productmolecular weight 422.78. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21366 |
|---|---|
| Actions | Agonist |
| CAS No. | 875787-07-8 |
| Formula | C21H12ClF5N2 |
| M. Wt | 422.78 |
| Purity | >98% |
| Synonyms | WAY 252623, WAY-252623, WAY252623, LXR623, LXR 623 |
| SMILES | ClC1=C(CN2N=C(C(C(F)(F)F)=CC=C3)C3=C2C4=CC=C(F)C=C4)C=CC(F)=C1 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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