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Catalog No.: A21366

LXRα and full LXRβ agonist


LXR-623 Chemical Structure

CAS NO. 875787-07-8

LXR-623 is a brain-penetrant partial LXRα and full LXRβ agonist, with IC50s of 24 nM and 179 nM, respectively.

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Biological Activity

LXR-623 is a brain-penetrant partial LXRα and full LXRβ agonist, with IC50s of 24 nM and 179 nM, respectively.
In vitro DMSO 76 mg/mL (179.76 mM)
Water Insoluble
Ethanol Warmed: 76 mg/mL (179.76 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.65 mL 118.26 mL 236.53 mL
0.5 mM 4.73 mL 23.65 mL 47.31 mL
1 mM 2.37 mL 11.83 mL 23.65 mL
5 mM 0.47 mL 2.37 mL 4.73 mL

*The above data is based on the productmolecular weight 422.78. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21366
Actions Agonist
CAS No. 875787-07-8
Formula C21H12ClF5N2
M. Wt 422.78
Purity >98%
Synonyms WAY 252623, WAY-252623, WAY252623, LXR623, LXR 623

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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