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LXR-623 is a brain-penetrant partial LXRα and full LXRβ agonist, with IC50s of 24 nM and 179 nM, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.65 mL | 118.26 mL | 236.53 mL |
| 0.5 mM | 4.73 mL | 23.65 mL | 47.31 mL |
| 1 mM | 2.37 mL | 11.83 mL | 23.65 mL |
| 5 mM | 0.47 mL | 2.37 mL | 4.73 mL |
*The above data is based on the productmolecular weight 422.78. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21366 |
|---|---|
| Actions | Agonist |
| M. Wt | 422.78 |
| Formula | C21H12ClF5N2 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 875787-07-8 |
| Synonyms | WAY 252623, WAY-252623, WAY252623, LXR623, LXR 623 |
| SMILES | ClC1=C(CN2N=C(C(C(F)(F)F)=CC=C3)C3=C2C4=CC=C(F)C=C4)C=CC(F)=C1 |
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