Fig. 1 · Structure
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LXR agonist 1
LXR Agonist
LXR Agonist 1 is a potent activator of Liver X Receptors (LXR-α and LXR-β), demonstrating AC50 values of 1.5 nM and 12 nM, respectively. This compound is valuable for investigating mechanisms related to lipid metabolism and atherosclerosis. Its ability to activate LXR pathways makes it a significant tool for research focused on cardiovascular diseases and related metabolic disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 1779524-90-1 |
| Applications | LXR Agonist |
| Formula | C27H26F3N3O3S |
| Molecular Weight | 529.57 |
| SMILES | CCC1=C(C2=CC=CC(OC3=CC(S(N(C)CCN)(=O)=O)=CC=C3)=C2)C4=CC=CC(C(F)(F)F)=C4N=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.