Fig. 1 · Structure

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LXRβ agonist-3

LXRβ Agonist

LXRβ agonist-3 is a selective agonist targeting liver X receptor β (LXRβ), exhibiting a potent EC50 of 0.095 μM. This compound demonstrates significant biological activity by inhibiting U87EGFRvIII cells with an IC50 of 3.75 μM. LXRβ agonist-3 is valuable for research applications focused on glioblastoma treatment and its antitumor efficacy.

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Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 2416049-12-0
Applications LXRβ Agonist
Formula C30H33N3O6S
Molecular Weight 563.66
SMILES
O=C1[C@]2(C3=CC=CC=C3N1)[C@@H](C4=CC(NC5=CC(S(C)(=O)=O)=C(C=C5)CO)=CC=C4)N(CC2)C(OC(C)(C)C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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