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LY 223592

Anticancer Agent

LY 223592 is a selective anticancer agent that functions as a derivative of Gemcitabine. It exhibits potent inhibitory activity against lung cancer cell proliferation, demonstrating an IC50 value of 5.6 nM in A549 cells, while showing low cytotoxicity towards normal cells. This compound is particularly relevant in research focusing on non-small cell lung cancer (NSCLC) and has potential applications in cancer therapeutic studies.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	103882-87-7
Applications	Anticancer Agent
Formula	C₁₀H₁₁F₂N₅O₄
Molecular Weight	303.22
Synonyms	dFdG
SMILES	O=C1C(N=CN2[C@H]3C(F)(F)[C@H](O)[C@@H](CO)O3)=C2NC(N)=N1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.