Fig. 1 · Structure
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LY-266500
SCS Inhibitor
LY-266500 is a potent inhibitor of succinyl CoA synthetase (SCS), demonstrating significant inhibitory effects on parasites such as Trypanosoma brucei brucei (IC50 = 0.6 μM) and Leishmania donovani (IC50 = 2.86 μM). This compound is valuable for research focused on parasitic infections, potentially aiding in the development of therapeutic strategies against these pathogens.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 147104-27-6 |
| Applications | SCS Inhibitor |
| Formula | C9H5ClFNOS |
| Molecular Weight | 229.66 |
| SMILES | O=C1C=CSN1C2=CC=C(C(Cl)=C2)F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.