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LY 274614

Catalog No.: A67302
NMDA Receptor Antagonist
LY 274614 is a competitive antagonist of the NMDA receptor, known for its oral bioactivity. This compound is essential for investigating neurological diseases, as it modulates excitatory neurotransmission and can help elucidate mechanisms underlying various neurological conditions. Its application in research supports the study of NMDA receptor-mediated pathways in both in vitro and in vivo models.
LY 274614 136109-04-1 NMDA Receptor Antagonist
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionLY 274614 is a competitive antagonist of the NMDA receptor, known for its oral bioactivity. This compound is essential for investigating neurological diseases, as it modulates excitatory neurotransmission and can help elucidate mechanisms underlying various neurological conditions. Its application in research supports the study of NMDA receptor-mediated pathways in both in vitro and in vivo models.
Product Information
Catalog NumA67302
FormulaC11H20NO5P
Molecular Weight277.25
CAS Number136109-04-1
SMILESO=C(O)[C@H]1NC[C@@]2(CC[C@@H](C[C@@]2(C1)[H])CP(O)(O)=O)[H]
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Neuronal Signaling > NMDA Receptors