LY 293284

Catalog No.: A29808
5-HT1A Receptor Agonist
LY 293284 is a highly selective agonist of the 5-HT1A receptor. It demonstrates notable biological activity by inducing a significant reduction in core temperature and increasing food intake in cholestatic rats following bile duct resection. This compound is valuable for research applications focused on the modulation of serotonergic pathways and studying the effects of 5-HT1A receptor activation in various physiological conditions.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionLY 293284 is a highly selective agonist of the 5-HT1A receptor. It demonstrates notable biological activity by inducing a significant reduction in core temperature and increasing food intake in cholestatic rats following bile duct resection. This compound is valuable for research applications focused on the modulation of serotonergic pathways and studying the effects of 5-HT1A receptor activation in various physiological conditions.
Product Information
Catalog NumA29808
FormulaC19H26N2O
Molecular Weight298.42
CAS Number141318-62-9
SMILESCC(C1=C2C3=C(C=C1)NC=C3C[C@@H](C2)N(CCC)CCC)=O
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