Fig. 1 · Structure
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LY-395153
iGluR
LY-395153 is an AMPA receptor enhancer, primarily targeting ionotropic glutamate receptors (iGluRs). It facilitates the binding to both natural and recombinant AMPA receptors, exhibiting variable binding influenced by AMPA receptor agonists. This compound serves as a valuable tool for elucidating regulatory sites of AMPA receptors, making it essential for research in neuropharmacology and understanding synaptic transmission dynamics.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 211313-51-8 |
| Applications | iGluR |
| Formula | C19H24N2O3S |
| Molecular Weight | 360.47 |
| SMILES | O=C(C1=CC=CC=C1)NC2=CC=C(C(CNS(=O)(C(C)C)=O)C)C=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.