Fig. 1 · Structure
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LY-517717
FXa Inhibitor
LY-517717 is a potent and orally bioavailable inhibitor of Factor Xa (FXa). This compound exhibits significant antithrombotic and anticoagulant properties, making it valuable for research applications focused on venous thromboembolism, particularly in the context of hip or knee replacement surgeries. Its effectiveness in targeting FXa positions LY-517717 as a promising candidate for further investigations in thrombotic disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 313489-71-3 |
| Applications | FXa Inhibitor |
| Formula | C27H33N5O2 |
| Molecular Weight | 459.58 |
| SMILES | O=C(N1CCN(C2CCN(C)CC2)CC1)[C@@H](C3=CC=CC=C3)NC(C(C=C4)=CC5=C4C=CN5)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.