LY2090314

Catalog No.: A12741

GSK-3 inhibitor

LY2090314

LY2090314 Chemical Structure

CAS NO. 603288-22-8

LY2090314 is a potent inhibitor of glycogen synthase kinase-3 (GSK-3) which plays an important role in many pathways, including initiation of protein synthesis, cell proliferation, cell differentiation, and apoptosis.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $100.00

Special Price $80.00

10 mg

Regular Price: $180.00

Special Price $144.00

25 mg

Regular Price: $350.00

Special Price $280.00

50 mg

Regular Price: $550.00

Special Price $440.00

10mM * 1mL in DMSO

Regular Price: $120.00

Special Price $96.00

Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

LY2090314 is a potent inhibitor of glycogen synthase kinase-3 (GSK-3) which plays an important role in many pathways, including initiation of protein synthesis, cell proliferation, cell differentiation, and apoptosis.
Targets
GSK-3β GSK-3α
0.9 nM1.5 nM
In vitro (25°C) DMSO 93 mg/mL (181.45 mM)
Water Insoluble
Ethanol Warmed: 2 mg/mL (3.9 mM)
In vivo 5% DMSO+45% PEG 300+ddH2O 16 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.51 mL 97.56 mL 195.11 mL
0.5 mM 3.9 mL 19.51 mL 39.02 mL
1 mM 1.95 mL 9.76 mL 19.51 mL
5 mM 0.39 mL 1.95 mL 3.9 mL

*The above data is based on the productmolecular weight 512.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12741
Actions Inhibitor
CAS No. 603288-22-8
Formula C28H25FN6O3
M. Wt 512.53
Purity >98%
Synonyms LY 2090314, LY-2090314
SMILES C1CCN(CC1)C(=O)N2CCN3C=C(C4=CC(=CC(=C43)C2)F)C5=C(C(=O)NC5=O)C6=CN=C7N6C=CC=C7
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy LY2090314 | LY2090314 Supplier | purchase | cost | manufacturer | order | distributor | buy 603288-22-8| 603288-22-8 Supplier | purchase 603288-22-8 | 603288-22-8 cost | 603288-22-8 manufacturer | order 603288-22-8 | 603288-22-8 distributor
Rewards