LY2090314

Catalog No.: A12741

GSK-3 inhibitor

LY2090314

LY2090314 Chemical Structure

CAS NO. 603288-22-8

LY2090314 is a potent inhibitor of glycogen synthase kinase-3 (GSK-3) which plays an important role in many pathways, including initiation of protein synthesis, cell proliferation, cell differentiation, and apoptosis.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $100.00

Special Price $80.00

10 mg

Regular Price: $180.00

Special Price $144.00

25 mg

Regular Price: $350.00

Special Price $280.00

50 mg

Regular Price: $550.00

Special Price $440.00

10mM * 1mL in DMSO
$120.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

LY2090314 is a potent inhibitor of glycogen synthase kinase-3 (GSK-3) which plays an important role in many pathways, including initiation of protein synthesis, cell proliferation, cell differentiation, and apoptosis.
Targets
GSK-3β GSK-3α
0.9 nM1.5 nM
In vitro DMSO 100 mg/mL (195.11 mM)
Water <1 mg/mL (<1 mM)
Ethanol 2 mg/mL heating (3.9 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.51 mL 97.56 mL 195.11 mL
0.5 mM 3.9 mL 19.51 mL 39.02 mL
1 mM 1.95 mL 9.76 mL 19.51 mL
5 mM 0.39 mL 1.95 mL 3.9 mL

*The above data is based on the productmolecular weight 512.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A12741
Actions Inhibitor
M. Wt 512.53
Formula C28H25FN6O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 603288-22-8
Synonyms LY 2090314, LY-2090314
SMILES C1CCN(CC1)C(=O)N2CCN3C=C(C4=CC(=CC(=C43)C2)F)C5=C(C(=O)NC5=O)C6=CN=C7N6C=CC=C7

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