Fig. 1 · Structure
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LY255582
Opioid Receptor Antagonist
LY255582 is a pan-opioid receptor antagonist, exhibiting high affinity for mu, delta, and kappa opioid receptors (Ki values of 0.4 nM, 5.2 nM, and 2.0 nM, respectively). This compound has been shown to reduce food intake and body weight, making it a valuable tool in obesity research. Its role in modulating opioid receptor activity offers potential insights into the mechanisms underlying appetite regulation and weight management.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 119193-09-8 |
| Applications | Opioid Receptor Antagonist |
| Formula | C22H35NO2 |
| Molecular Weight | 345.52 |
| SMILES | OC1=CC([C@]2([C@H](CN(CC2)CC[C@@H](C3CCCCC3)O)C)C)=CC=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.