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LY2562175

Catalog No.: A17016

FXR agonist

LY2562175

LY2562175 Chemical Structure

CAS NO. 1103500-20-4

LY2562175 is a potent and selective FXR agonist in vitro and has robust lipid modulating properties, lowering LDL and triglycerides while raising HDL in preclinical species.

Availability: In stock

Package Price Qty
2 mg

Regular Price: $220.00

Special Price $176.00

5 mg

Regular Price: $450.00

Special Price $360.00

10 mg

Regular Price: $675.00

Special Price $540.00

50 mg

Regular Price: $1,890.00

Special Price $1,512.00

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Biological Activity

LY2562175 is a potent and selective FXR agonist in vitro and has robust lipid modulating properties, lowering LDL and triglycerides while raising HDL in preclinical species.
In vitro DMSO 91 mg/mL (168.38 mM)
Water Insoluble
Ethanol 1 mg/mL (1.85 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.5 mL 92.52 mL 185.03 mL
0.5 mM 3.7 mL 18.5 mL 37.01 mL
1 mM 1.85 mL 9.25 mL 18.5 mL
5 mM 0.37 mL 1.85 mL 3.7 mL

*The above data is based on the productmolecular weight 540.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17016
Actions Agonist
CAS No. 1103500-20-4
Formula C28H27Cl2N3O4
M. Wt 540.44
Purity >98%
Synonyms LY 2562175, LY-2562175
SMILES O=C(C1=CN(C)C2=C1C=CC(N3CCC(OCC4=C(C5CC5)ON=C4C6=C(Cl)C=CC=C6Cl)CC3)=C2)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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