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LY303336

Polysubstituted 4-aminoimidazole AT1 Receptor Antagonist

LY303336 is a polysubstituted 4-aminoimidazole derivative that acts as an antagonist of the AT1 receptor, exhibiting a potent inhibition with an IC50 value of 5.2 nM. This compound is primarily utilized in cardiovascular research to study the effects of AT1 receptor modulation on blood pressure and fluid balance. Its application extends to investigating the role of AT1 receptor antagonism in various pathological conditions, making it a valuable tool for studying cardiovascular and renal physiology.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	157187-00-3
Applications	Polysubstituted 4-aminoimidazole AT1 Receptor Antagonist
Formula	C₃₀H₃₇N₄O₁₁PS
Molecular Weight	692.67
SMILES	CCCCCC[C@@H](N1C=C(N=C1)NC(C2=C(C=CC=C2)S(=O)(O)=O)=O)C(N3[C@@H](C[C@@H](C3)OC4=CC=C(C=C4)CP(O)(O)=O)C(O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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LY303336

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LY303336 25 mg