LY334370 fumarate

Catalog No.: A29962
5-HT Agonist
LY334370 fumarate is a selective agonist for the 5-HT1F receptor, exhibiting a Ki value of 1.6 nM. This compound is utilized in research to investigate its role in modulating serotonin signaling pathways and assessing potential therapeutic applications in neurological disorders. Its specific action on the 5-HT1F receptor makes it a valuable tool for studies focused on migraine treatment and other serotonin-related conditions.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionLY334370 fumarate is a selective agonist for the 5-HT1F receptor, exhibiting a Ki value of 1.6 nM. This compound is utilized in research to investigate its role in modulating serotonin signaling pathways and assessing potential therapeutic applications in neurological disorders. Its specific action on the 5-HT1F receptor makes it a valuable tool for studies focused on migraine treatment and other serotonin-related conditions.
Product Information
Catalog NumA29962
FormulaC25H26FN3O5
Molecular Weight467.49
CAS Number182563-09-3
SMILESO=C(C1=CC=C(F)C=C1)NC2=CC3=C(C=C2)NC=C3C4CCN(C)CC4.O=C(O)/C=C/C(O)=O
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