Fig. 1 · Structure

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(±)-LY395756

mGlu2 Receptor Agonist

(±)-LY395756 is a potent agonist of the mGlu2 receptor and an antagonist of the mGlu3 receptor. This compound selectively engages the native mGlu2 and mGlu3 receptors, making it a valuable tool for studying glutamate receptor signaling pathways. Its unique pharmacological profile positions it for applications in neurological research and the exploration of potential therapeutic strategies targeting mGlu receptor subtypes.

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Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 852679-66-4
Applications mGlu2 Receptor Agonist
Formula C9H13NO4
Molecular Weight 199.20
SMILES
O=C([C@@]1(N)[C@]2([H])[C@@H](C(O)=O)[C@]2([H])[C@H](C)C1)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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