Fig. 1 · Structure
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LY56110
Aromatase Inhibitor
LY56110 is an orally active aromatase inhibitor that selectively targets the aromatase enzyme, playing a crucial role in estrogen synthesis. It exhibits significant inhibitory effects on P-450-dependent O-demethylation activities, as evidenced by IC50 values of 2.5 μM for p-nitroanisole and 11 μM for ethylmorphine in rat hepatic microsomes. This compound is applicable in research focused on neurological disorders and may provide insights into hormone-related pathologies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 26766-37-0 |
| Applications | Aromatase Inhibitor |
| Formula | C17H12Cl2N2 |
| Molecular Weight | 315.20 |
| SMILES | ClC1=CC=C(C=C1)C(C2=CC=C(C=C2)Cl)C3=CN=CN=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.